Arsip Mailing List Dokter Umum: Re: [Dokter Umum] Re: EtoxiSclerol

Jadi semuanya tergantung anda bukan, karena yg meneyelesaikan supaya
tubuh anda menajdi apa? ya anda sendiri

Amani Goland wrote:
> --- In dokter_umum@yahoogroups.com, "Dr.(Naturopathy) Ir. Donny
> Hosea MBA. PhD." <puyuh23@...> wrote:
>
>> Hello,
>> Barangkali ini membantu?
>> Bacalah semua sampai akirnya.
>>
>>
>
> Hello juga Dok. dan terimakasih atas kiriman artikelnya.
>
> Terkait tulisan dibawah ini.
>
> Apah yah maksud dari :
>
> 1. Reaksi anaphylactic
>
Reaksi spontant tubuh terhadap alergi yg bisa menyerang berbagai
tempat/oragn ditubuh:
Saluran pernapasan, kulit, paru2, jantung, perut dlsbnya. sign nya
sendiri a/l seperti disebutkan dibawah ini dg probaliti penyerangannya:

Frequency of Signs and Symptoms:

Signs and symptoms Frequency (%)

Urticaria, angioedema 88
Dyspnea, wheeze 47
Dizziness, syncope, hypotension 33
Nausea, vomiting, diarrhea, cramping abdominal pain 30
Flush 46
Upper airway edema 56
Headache 15
Rhinitis 16
Substernal pain 6
Pruritus without rash 4.5
Seizure 1.5

Adapted from Lieberman P. Anaphylaxis and anaphylactoid reactions. In:
Middleton E, ed. Allergy: principles and practice. 5th ed. St. Louis:
Mosby, 1998:1079-89
> 2. hyperpigmentation
>
Perubahan warna kulit, bertambah gelab, bisa juga berkerak n menebal
> 3. Resep yang diberikan oleh dokter kepada saya adalah EtoxySclero
> type yang 2 %. dimana kandungan Polidacanol nya 40 mg, dan etanol
> 0.10 ml per ampul. Dokternya meminta disediakan 2 ampul. Kira2 cukup
> aman ngak yah komposisi seperti itu.
>
Tdk tau apakah aman atau tdk karena akan bergantung pada reaksi tubuh ybs.
Yg jelas dg kemungkinan 56 % of upper air way endema, saya pikir cukup
berbahaya, ybs bisa megab2 kalau ini terjadi, kalau cuman bentol2 ya
barangkali masih bisa di tolerir walau cukup tdk nyaman saja bagi tubuh
> PS : Sorry banyak nanya. Soalnya menerjemahkan bahasa inggrisnya
> saja saya sudah kesulitan, apalagi ditambah istilah istilah
> kedokteran lagi :)
>
>
>
>
> _/*Etoxisclerol*/_^® , Sotrauerix^® , Laureth 9^® ). All
> commercially available formulations contain some small
> quantity of ethanol. The drug was originally developed and
> marketed in the 1950s under the name Sch 600^® as a
> non-amide, non-ester local anaesthetic that was useful for
> injected local anaesthesia as well as for epidural
> anaesthesia and for topical mucosal anaesthesia. It was
> first used as a sclerosing agent in Germany in the 1960s,
> and was quickly adopted for that use in most countries. The
> drug is not yet approved by the FDA for sale in the United
> States as a sclerosing agent, but is nonetheless widely used
> because it offers certain advantages over many other
> available drugs. As a local anaesthetic, Polidocanol is
> painless upon injection. It does not produce necrosis if
> injected intradermally, and has been reported to have a very
> low incidence of allergic reactions. The drug has been
> intensely studied and extremely well characterized, and has
> a high therapeutic index. The LD50 in rabbits is 200 mg/kg
> (approximately 5 times greater than that of novocaine), and
> the LD50 in mice is even greater, at 1200 mg/kg. *For human
> use the German manufacturer of polidocanol recommends a
> maximum daily dose of 2 mg per kg, although at least one
> author has reported the routine use of much higher doses.
> For all its advantages, polidocanol is not without problems
> as a sclerosant. Occasional anaphylactic reactions have been
> reported. In some patients it may produce hyperpigmentation,
> although to a lesser extent than many other agents.
> Telangiectatic matting after sclerotherapy with polidocanol
> is as common as with any other agent.*
>
>